Life Extension Homocysteine Resist Vegetarian B‑Vitamin Complex, 60 Capsules — Bioactive B2 B6 B12 Folate

Life Extension Homocysteine Resist is a vegetarian B-vitamin complex formulated to help maintain already normal homocysteine levels for heart and brain health.

This two-month supply contains 60 gluten-free, vegetarian capsules combining bioactive forms of B2 (riboflavin), B6 (pyridoxal-5'-phosphate), B12 (methylcobalamin) and folate as L-5-MTHF. Made in the USA from non-GMO ingredients, the formula focuses on the specific B vitamins most often linked in research to support healthy homocysteine metabolism and overall cardiovascular and cognitive wellness. It's packaged for convenient daily use and intended as an adjunct to a balanced diet and lifestyle.

How does this supplement support normal homocysteine levels?

The capsule blend supplies four bioactive B vitamins that participate in the metabolic pathways that keep homocysteine within the normal range. Each nutrient plays a complementary role in converting homocysteine to benign compounds, supporting efficient methylation and amino acid recycling.

• Riboflavin (B2) supports enzyme systems involved in homocysteine metabolism.
• Pyridoxal-5'-phosphate (active B6) assists in transsulfuration pathways.
• Methylcobalamin (active B12) donates methyl groups for remethylation.
• L-5-MTHF (bioactive folate) directly supports methylation reactions.

What forms of B vitamins are used and why does that matter?

Life Extension uses bioactive, readily utilized forms of B vitamins to improve absorption and cellular availability. Using methylcobalamin for B12 and L-5-MTHF for folate bypasses several conversion steps that some people find less efficient, which can improve consistent nutrient delivery.

• Methylcobalamin is a naturally active B12 form better retained in tissues.
• L-5-MTHF is the metabolically active folate used directly in methylation.
• Pyridoxal-5'-phosphate is the active coenzyme form of B6.
• Riboflavin supports cofactors needed for vitamin activation.

How should I take these vegetarian capsules and what results can I expect?

The product is designed for daily use; follow the label directions for dosing. Because homocysteine and nutritional status change gradually, measurable shifts in biomarkers may take weeks to months, and individual responses vary based on diet, genetics and existing nutrient levels.

• Take as directed on the product label, with food to aid absorption.
• Allow weeks to months for nutritional changes to show in lab tests.
• Consider discussing baseline and follow-up bloodwork with your healthcare provider.
• Combine with a varied diet rich in B-vitamin sources for best effects.

Are there quality assurances and who manufactures this product?

Life Extension manufactures Homocysteine Resist in the USA using predominantly non-GMO, gluten-free ingredients and provides Certificates of Analysis for transparency. The product is produced under quality control standards to ensure ingredient identity and purity.

• Made in the United States with globally sourced components.
• Contains 100% non-GMO ingredients and is gluten-free.
• Certificates of Analysis available for batch verification.
• Vegetarian capsule form suitable for non-meat diets.

Who is this for: Homocysteine Resist is intended for adults seeking targeted B-vitamin support to help maintain already normal homocysteine levels and support cardiovascular and cognitive wellness as part of a healthy lifestyle. It is suited to vegetarians and people who prefer bioactive vitamin forms or who are looking for a non-GMO, gluten-free supplement produced in the USA. Those with specific medical conditions, taking medications, or who are pregnant or nursing should consult a healthcare professional before starting any new supplement regimen.

Ingredients

Riboflavin (vitamin B2) 25 mg Vitamin B6 (as pyridoxyl 5’-phosphate) 100 mg Folate (as L-5-methyltetrahydrofolate calcium salt) 8500 mcg° Vitamin B12 (as methylcobalamin) 1000 mcg Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule), stearic acid, silica, rice extract blend. °DFE (Dietary Folate Equivalents).