Pure Encapsulations MethylAssist methylation support supplement, 90 capsules — methylfolate & active B12

Pure Encapsulations MethylAssist is a concentrated B-vitamin formula featuring Metafolin L-5-MTHF plus activated B6, B12, and benfotiamine to support healthy methylation and cellular function.*

This targeted supplement combines bioactive forms of key B vitamins in a single capsule designed for people seeking reliable methylation support and foundational nutrient coverage. Crafted by Pure Encapsulations, MethylAssist delivers methylfolate (Metafolin L-5-MTHF), methylcobalamin, pyridoxal 5'-phosphate (active B6), and benfotiamine alongside a complementary B-vitamin complex. The formulation is produced without common allergens, unnecessary additives, or GMOs, making it suitable for sensitive users who prefer minimal-ingredient products.

How does MethylAssist support methylation and folate status?

MethylAssist supplies L-5-MTHF, the metabolically active form of folate, which bypasses several conversion steps required by folic acid. Providing folate in this form can help maintain usable folate pools for cellular processes that rely on methyl groups. The product also pairs folate with methylcobalamin to reinforce one-carbon metabolism pathways.

• Contains Metafolin L-5-MTHF, the active folate form
• Includes methylcobalamin for direct B12 activity
• Formulated to support one-carbon and methylation processes

Which active B vitamins are included and why do they matter?

MethylAssist uses bioavailable, coenzyme forms: pyridoxal 5'-phosphate (active B6), methylcobalamin (active B12), and benfotiamine (a lipid-soluble thiamine derivative). These forms are selected to be readily used by the body without extra conversion steps, which can be helpful for those with genetic variations affecting B-vitamin metabolism. Together they support enzymatic reactions tied to energy, neurotransmitter synthesis, and cellular maintenance.

• Activated B6 supports neurotransmitter-related pathways
• Methylcobalamin supplies direct B12 activity for cellular processes
• Benfotiamine offers a highly absorbable form of thiamine

What additional wellness areas does MethylAssist target?

This formula is positioned for users looking for broad nutrient support related to cardiovascular and neurological wellbeing. While not a treatment, the included B-vitamin complex contributes to physiological systems involved in cardiovascular function and neural health. The combination of methylfolate and active B12 can be particularly relevant where folate and B12 interplay matters.

• Supports nutritional elements tied to cardiovascular maintenance
• Provides nutrients commonly associated with neuronal support
• Formulated without common allergens and artificial additives

How should I take MethylAssist and what should I check before use?

Follow the label directions or your healthcare practitioner's recommendation for dosing. Because it contains active forms of folate and B12, consult a clinician if you are pregnant, nursing, taking medications, or have a medical condition. Store the bottle in a cool, dry place and keep out of reach of children.

• Take as recommended on the product label or by a healthcare professional
• Check with a clinician if you are pregnant, nursing, or on medication
• Store in a cool, dry area; keep away from children

Who is this for: Pure Encapsulations MethylAssist is intended for adults seeking a concentrated, research-informed B-vitamin supplement with methylfolate and activated B vitamins. It is a practical option for those who prefer minimal-ingredient formulations, people with dietary restrictions or sensitivities, and anyone wanting targeted methylation and one-carbon nutrient support as part of a broader wellness strategy.*

Ingredients

Each serving size (1 capsule) contains: Vitamin B6 (as pyridoxal 5’ phosphate) 16 mg, Folate (as Metafolin, L-5-MTHF) 1667 mcg DFE, Vitamin B12 (as methylcobalamin) 1000 mcg, BenfoPure benfotiamine 75 mg. Other ingredients: hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water).