Pure Encapsulations PureGenomics B-Complex 120 Capsules — Activated B Vitamins with L-5-MTHF & Coenzyme B12/B6

Pure Encapsulations PureGenomics B-Complex is an activated B-vitamin formula designed to supply bioavailable forms of B vitamins to support methylation-related pathways and general cellular metabolism.

This specialized B-complex delivers methylation-aware nutrients in their active forms, including L-5-MTHF and coenzyme forms of B12 and B6, created for people who want targeted B vitamin support. The formula aims to provide forms of B vitamins that are easier for many bodies to use, while avoiding common fillers, allergens, and unnecessary additives. Each bottle contains 120 capsules, offering a convenient supply for regular supplementation.

How does this B-complex address methylation differences?

The formula supplies methylation-friendly forms of folate and related cofactors so they’re ready for cellular use without additional conversion steps. By featuring L-5-MTHF and active B6 and B12 forms, it supports pathways commonly affected by genetic variants involved in methylation.

• Includes 800 mcg L-5-MTHF (active folate)
• Provides adenosylcobalamin and hydroxocobalamin as B12 sources
• Contains activated pyridoxal phosphate (vitamin B6) and riboflavin (B2)
• Formulated for people with common genetic variations affecting folate/B vitamin processing

Which active B vitamin forms are included and why do they matter?

This product emphasizes coenzyme and reduced forms of B vitamins that bypass some metabolic activation steps. Those ready-to-use forms can be particularly useful for individuals who have reduced enzyme activity or who prefer pre-activated nutrients.

• L-5-MTHF provides bioactive folate instead of folic acid
• Adenosylcobalamin and hydroxocobalamin offer complementary B12 physiology
• Pyridoxal phosphate supplies the active form of vitamin B6
• Benfotiamine included as a lipid-soluble thiamine derivative

How will this B-complex fit into a daily routine?

Take the capsules with food according to the label or a healthcare provider’s guidance to support absorption and tolerance. The bottle’s 120-count format is intended for multi-week use at typical daily serving sizes, making it easy to maintain consistency.

• 120 capsules per bottle for routine supplementation
• Take with meals to reduce stomach upset if needed
• Dosage can be adjusted under professional direction
• Suitable for stacking with other targeted nutrients when recommended

What does Pure Encapsulations leave out of this formula?

Pure Encapsulations highlights ingredient clarity by excluding common allergens and unnecessary additives. The brand focuses on hypoallergenic manufacturing and avoids artificial colors, flavors, and genetically modified organisms.

• Free from gluten, dairy, and common allergens
• No artificial colors, flavors, or unnecessary excipients
• Non-GMO ingredient sourcing and transparent labeling
• Manufactured under quality-focused standards

Who is this for: PureGenomics B-Complex is aimed at adults seeking a B-vitamin supplement formulated with activated and methylation-aware ingredients. It may be appropriate for those who prefer bioactive vitamin forms, people interested in supporting one-carbon and energy metabolism pathways, and anyone avoiding common allergens or unnecessary additives. Always consult a healthcare professional before beginning a new supplement, especially if you are pregnant, nursing, taking medications, or managing medical conditions.

Ingredients

Each serving size (1 capsule) contains: Thiamin 25 mg, Riboflavin 15 mg, Niacin 50 mg, Vitamin B6 50 mg, Folate 1333 mcg DFE, Vitamin B12 800 mcg, Biotin 400 mcg, Pantothenic acid 100 mg, Choline 40 mg, Inositol 25 mg, Benfopure benfotiamine 3 mg. Other ingredients: vegetarian capsule (cellulose, water), hypoallergenic plant fiber, ascorbyl palmitate.